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Aplastic Anaemia and Myelodysplasia Glossary > Glossary > Myelofibrosis

MYELOFIBROSIS -
Noun: A progressive disease of the bone marrow where neoplastic bone marrow stem cells lodge and grow in multiple sites outside the bone marrow. Typically, there is enlargement of the spleen and a gradual replacement of the bone marrow elements by fibrosis (scarring), progressive anaemia and variable changes in the number of white blood cells and platelets. Diagnosis is by bone marrow biopsy . There is no definitive treatment for the disorder that has been shown to affect life span favourably.

Greek - myelós = marrow +
Latin - fibra = fiber +
Greek - osis = an abnormal condition.

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