IMMUNOGLOBULIN -
Noun: Antibodies are often referred to as immunoglobulins. The infecting agents, or antigens are presented to the B lymphocytes by the T lymphocytes , prompting the B cells to mature and produce one of five antibody patterns: Immunoglobulin G (IgG), IgA, IgM, IgD or IgE.

IgG is the most abundant antibody, making up 75 percent of all those in blood plasma . It is most active in the blood, lymph and intestines. Neutrophils and macrophages have receptor sites for the IgG antibody and so can attach and eat the antibody and its captives when it is ready.

IgG is required by cells which are active in destroying cancer cells, although, unfortunately, the same cells are also involved in transplant rejection and autoimmune diseases.

IgA is an antibody found in the blood serum and in the mucous secretions of the respiratory, urinary, and intestinal organs where exposure to foreign substances is common. It defends the body against micro-organisms by combining with a protein in the mucous. People who suffer from food allergy problems probably have a malfunctioning IgA; they become oversensitive to certain foods which, in any other person, would not be harmful.

IgM is the largest and most primitive immunoglobulin. Its size makes it useful for picking up lots of small antigens, which it can manage 10 at a time. It is particularly important early on in any immune response.

IgD is found in blood serum in small amounts but increases during allergic reactions.

IgE is attracted to cells involved in allergic response and basophils. It is found primarily in the lungs, skin and mucous membranes. It is associated with all forms of allergy, including hayfever, asthma, hives, itching, etc. People who suffer from allergies usually make too much IgE.

Latin - in = not +

Latin - munis = obliging +

Latin - globulus = globe (as in anything rounded like a globe)

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