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Aplastic Anaemia and Myelodysplasia Glossary > Glossary > Haplo Transplant

HAPLO TRANSPLANT -
Noun: When doing a Class 1 and a Class 2 Tissue typing it is found that each individual has two sets of each 'A', 'B', 'Cw' and 'DR' antigens. These antigens are genetic markers on the surface of the white blood cells. One set of A, B, Cw and DR is inherited from the father and one set of A, B, Cw and DR antigens are inherited from the mother. Each set of A, B, Cw, and DR antigens is known as a haplotype. Each individual has two haplotypes. With only rare exceptions, each parent will be haplo-compatible, or half-matched, with his or her child. This enables the patient to have a bone marrow transplant when there are no brothers or sisters or none are compatible. The stem cells must be specially treated before they are transplanted into the patient which bring about advantages and disadvantages. These should be discussed with your doctor.

Greek - haploûs = single


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