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Aplastic Anaemia and Myelodysplasia Glossary > Glossary > Amphotericin

AMPHOTERICIN -
Noun: An antifungal antibiotic which is not absorbed by the gut so it must be injected. It is active against most deep-seated yeast and fungal infections. Diet advice given by the British Medical Association says that when given by injection, Amphotericin may reduce the levels of potassium and magnesium in the blood. To correct this, mineral supplements may be recommended. If taken while taking Cyclosporin ( an immunosuppressant drug used to handle AA & MDS ) there is an increased likelihood of kidney damage. Diet advice on Cyclosporin advises one to avoid high-potassium foods and potassium supplements so I can see a problem taking the two drugs at the same time. Inform your doctor immediately if you notice any pain in urinating or blood in the urine. Corticosteroids are also sometimes used in the treatment of AA & MDS and if taken with Amphotericin may increase the loss of potassium from the body. Common side-effects of amphotericin are fever, nausea, headache and vomiting.

Greek - amphóteros = both (yeast and fungi)


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